There are many different ways of taking cannabidiol. There are capsules, tinctures, etc. With e-cigarettes becoming very popular lately amongst cigarette smokers, the use of vaporizers has also branched out into our world of natural health. They are now counted as one of the convenient and beneficial ways of taking CBD.
That being said, there are few factors you should look out for before buying buying CBD product in any form.
There seems to be a lot of infographics online that give dosage information, but what you need to remember is that everyone is different and metabolisms vary. Like with all news things, be reasonable and start small, working up the dosage based on how you feel until you find the desired effect.
Like all new things relating to the vape world its open to abuse and unfortunately there are a lot of of CBD producers who are using synthetic CBD so be very careful when buying cleverly marketed CBD vape liquids as the quality and product could actually be harmful to you as unknown compounds etc are introduced to your body. So only buy from certified vendors or make your own to be sure of the quality.
Cheap cannabidiol, (CBD) oils are cheap for a reason. If you searched for ‘CBD oil’ in your search engine right now it would bring up hundreds of different CBD products – and all of them claiming to be the best ever and extracted from the strongest hemp! The interesting thing about them is that most of these producers and distributors offer no tangible evidence to support the claim that their products are the best. Surely, lower prices are more attractive, but think twice before picking the cheap CBD oil over the higher quality one. If you want to make sure you’re getting a safe and effective product, look for quality, not for a low price.
Most importantly, do your research before buying any CBD products. Look out for lab test results that are visible for anyone who wants to see them. Beware of products that claim to cure everything – although cannabidiol has shown promising results in numerous studies, that doesn’t mean to say that it will cure your condition over night!
Glioma is the term used to describe a tumor that originated on the brain or spine. Each year, 10,000 Americans are diagnosed with malignant glioma. Of those, about half will die within a year of diagnosis. Only 25 percent are still alive after two years.
Researchers Investigated Glioma & Its Reaction To Cannabinoids
Most often occurring in the brain, malignant gliomas are rarely curable despite years of research on the subject. Traditional therapies like radiotherapy and chemotherapy have had limited success, and glioma’s ability to spread to normal tissue makes surgery difficult.
“Each year, 10,000 Americans are diagnosed with malignant glioma.”
With that said, the mechanism of action that cannabidiol (CBD)influences is not very well understood. A study published last week in PLOS ONEoffers some insight into what may be happening.
Cannabidiol (CBD) May Treat Glioma Through Multiple Pathways
A team of researchers from Italy and Canada previously determined that cannabidiol (CBD) effectively limits human glioma cell growth. Nonetheless, their findings left more to be explained. “Studies exploring the putative anti-invasive properties of CBD in glioma cells are still limited and the molecular mechanisms underlying its effect are poorly understood,” they wrote.
In turn, the same research team conducted a cell-culture study to characterize how cannabidiol (CBD) is able to inhibit the growth of two different glioma cell lines (U87-MG & T98G). Additionally, they investigated the compound’s influence on a number of proteins tied to the spreading of tumors.
“Cannabidiol (CBD) affects multiple tumoral features and molecular pathways.”– Daniela Parolaro
The investigators used cannabidiol (CBD), which was provided by GW Pharmaceuticals, to treat glioma cells in vitro. According to their results, CBD was able to significantly decrease the invasiveness of each cell model. They also found that cannabidiol (CBD) may induce cancerous cell death, depending on its dosage concentration.
Furthermore, the researchers determined that cannabidiol (CBD) caused a decreased expression of various proteins involved in the spread of glioma. Yet again, this result was dependent on the dosage administered. CBD seemed to down-regulate pro-survival signaling pathways in each of the glioma cell models as well.
In conclusion of the study, the research team noted that their results “provide new insights into the anti-tumor action of CBD.” Their report went on to say, “this cannabinoid affects multiple tumoral features and molecular pathways.”
Of course, more research will be necessary to facilitate whether cannabidiol (CBD) is a viable treatment for glioma. GW Pharmaceuticals recently commenced clinical trials for the cannabis-based drug Sativex to determine it’s ability to treat Recurrent Glioblastoma Multiforme (GBM) – a particularly aggressive type of brain cancer. It is the first study on cannabis-based cancer treatment with humans.
If you’re unfamiliar with cannabinoids or terpenoids, it’s time to learn. Each strain can be defined by a specific chemical makeup, i.e.., its combination of cannabinoids and terpenoids. The exact relationship between cannabinoids and terpenoids is uncertain, but the ineffectiveness of single cannabinoid extractions (e.g.., Marinol THC capsules) prove the significance of the synergistic effects of both compounds – often referred to as “the entourage effect.” Whether terpenes increase bioaccessibility of cannabinoids or vice versa, terpenes have been connected to the flavor and aroma of the plant whereas cannabinoids are well-known to influence effects.
So what exactly are terpenes?
Terpenes are volatile aromatic molecules that evaporate easily and readily announce themselves to the nose. Various researchers have emphasized the pharmacological importance of terpenes, or terpenoids, which form the basis of aromatherapy, a popular holistic healing modality. Marijuana’s compelling fragrance and particular psychoactive flavor are determined by the predominate terpenes in a strain.
Around 200 terpenes have been found in cannabis, but only a few of these odiferous oily substances appear in amounts substantial enough to be noteworthy, or nose worthy, as it were. Among them are monoterpenes, diterpenes, and sesquiterpenes, which are characterized by the number of repeating units of a 5-carbon molecule called isoprene, the structural hallmark of all terpenoid compounds. The terpenes in marijuana have given the plant an enduring, evolutionary advantage. Pungent terpenoid oils repel insects and animal grazers; others prevent fungus.
Terpenes, it turns out, are healthy for people as well as plants. A September 2011 report by Dr. Ethan Russo in the British Journal of Pharmacology discussed the wide-ranging therapeutic attributes of terpenoids, which are typically lacking in “CBD-only” products.
What are marijuana terpenes?
More than 100 different terpenes have been detected in marijuana, and there are many more if we consider the different variations of each one. For example, the typical smell of citrus fruits comes from terpenes called limonenes, but these can vary in concentration. The limonenes of a lemon are identical to the limonenes of an orange, but each variety is defined by a different smell, resulting from tiny differences in the proportions or the form of the limonenes that it contains.
Here we list the main terpenes found in Cannabis Sativa and its effects on our health. You will see that percentages can vary widely from one variety to another. Here are the most common cannabis cannabinoids and their benefits:
THC is the most well-known and most abundant cannabinoid in marijuana, THC is the cannabinoid responsible for the main psychoactive effects most people associate with marijuana. THC has analgesic, anti-emetic (reduces vomiting and nausea), anti-proliferative (inhibits cancer cell growth), antioxidant, antispasmodic, anxiolitic (decreases anxiety), appetite stimulant, euphoriant, and neuroprotective (slows damage to the nervous system and brain) effects.
CBD is the main non-psychoactive cannabinoid in cannabis. CBD has a wide range of therapeutic uses. Because of its many therapeutic uses and because it is non-psychoactive, it is often recommended for treatment of children, the elderly, and anyone who wants the medicinal benefits of cannabis without the “high.” CBD has analgesic, antibacterial, anti-diabetic (reduces blood sugar), antidepressant, anti-emetic, anti-epileptic, anti-inflammatory, anti-insomnia, anti-ischemic (reduces the risk of artery blockage), antipsoriatic (treats psoriasis), anti-proliferative, antipsychotic, antioxidant, antispasmodic, anxiolitc, bone stimulant, immunosuppressive, intestinal anti-prokinetc (reduces small intestine contractions), neuroprotective, and vasorelaxant (reduces vascular tension) effects.
CBN is a mildly psychoactive cannabinoid that comes from the degradation of THC after an extended period of time due to exposure to oxygen and heat. There is usually very little to no CBN in a fresh plant. CBN has analgesic, anti-epileptic, antibacterial, anti-inflammatory, anti-insomnia, anti-emetic, anti-proliferative, appetite stimulant, and bone stimulant effects.
CBG is a non-psychoactive cannabinoid that is believed to block the psychoactive effects of THC. CBG has analgesic, antibacterial, anti-epileptic, anti-inflammatory, anti-insomnia, anti-proliferative, bone stimulant, and neurogenic (promotes growth of new brain cells) effects.
CBC is a non-psychoactive cannabinoid. CBC has a wide range of medical uses. CBC has analgesic, antidepressant, antifungal, anti-inflammatory, anti-proliferative, bone stimulant, anxiolitic, and neurogenic (promotes the growth of new brain cells) effects.
THCA is the most abundant cannabinoid in cannabis. THCA is the acidic precursor to THC and converts to Δ9-THC when heated. THCA is non-psychoactive and has many therapeutic uses. THCA is an analgesic, a neuroprotectant has anti-inflammatory, anti-insomnia, antispasmodic, anti-proliferative, and anti-emetic effects, and has been shown to modulate the immune system.
CBDA is found in elevated levels in specific cannabis strains. Like THCA, CBDA converts to CBD when heated. CBDA is non-psychoactive and has antibacterial and anti-inflammatory properties and has also been shown to be anti-inflammatory, anti-emetic, and anti-proliferative.
The benefits of the primary terpenes found in cannabis:
Pinene is the most common naturally occuring terpenoid in nature and is responsible for the pine taste in many popular strains. Pinene is a bronchodilator and has analgesic, antibacterial, anti-inflammatory, anti-prolifertive, and anti-oxidant effects.
Linalool has a floral scent with spicy overtones and has analgesic, antidepressant, anti-epileptic, anti-inflammatory, anti-psychotic, anxiolytic, and sedative effects.
Myrcene is the smallest terpene but the most prevalent terpene found in most varieties of cannabis. Myrcene dictates whether a strain will have an indica or sativa effect. Strains high in myrcene will result in a “couch lock” effect while strains with low levels of Myrcene will produce a more energetic high. Myrcene has earthy, fruity notes and analgesic, antibacterial, anti-diabetic, anti-inflammatory, anti-insomnia, anti-proliferative/ant-mutagenic, antipsychotic, and antispasmodic effects.
Limonene is a dominant terpene in strains that have a pronounced sativa effect. Limonene has a strong citrus odor and flavor and aids in the absorption of other terpenes through the skin and mucous membranes. It has antidepressant, antifungal, anti-inflammatory, anti-proliferative, anxiolytic, gasto-pesphageal reflux (reduces acid reflux), immunostimulant effects.
Caryophyllene is a spicy terpene. It is the only terpene known to interact with the body’s endocannabinoid system (CB2). Caryophyllene has analgesic, antibacterial, antidepressant, anti-inflammatory, anti-proliferative, antioxidant, anxiolitic, analgesic, and neuroprotective effects.
Humulene contributes to the “hoppy” aroma of cannabis. Humulene has analgesic, antibacterial, anti-inflammatory, anti-proliferative, and anorectic (appetite suppressant) effects.
Bisabolol has a light, sweet floral aroma and is known to have antimicrobial, anti-inflamatory, and anti-irritant effects. Bisabolol has also shown to be a pro-apoptotic agent for acute leukemia cells.
Ocimene is used in perfumes for its pleasant odor. In nature this terpene acts as part of the plants defenses and possesses antifungal properties.
Terpinolene has smoky or woody notes. Terpinolene is a sedative and also has antibacterial, anti-fungal, anti-insomnia, anti-proliferative, and antioxidant effects.
Geraniol has rosy, floral notes. It is an effective mosquito repellent and shows a potential protective effect against neuropathy.
Terpineol smells of lilac, crabapple blossoms and lime blossoms. During tests on mice, their mobility was reduced to 45%. This explains the sedative effect of some marijuana strains. Terpineol is often found in strains that have a high level of pinenes, the aromas of which can hide the smell of terpineol.
Valencene contributes to the citrus odor of cannabis. The effects of Valencene are being researched.
Selina-3, 7 (11)-diene is a more recently discovered terpene whose properties are still being explored. It has been used in various antimicrobial studies in essential oil testing and has shown promise with inhibiting microbial growth.
From clothing, to food, to fuel, to a whole host of consumer and building products, not to mention helping in cleaning up soil pollution, it’s only slightly hyperbole to call hemp a wonder crop.
Industrial hemp has many uses, including paper, textiles, biodegradable plastics, construction, health food, and fuel. It is one of the fastest growing biomasses knownand one of the earliest domesticated plants known. It also runs parallel with the “Green Future” objectives that are becoming increasingly popular. Hemp requires little to no pesticides no herbicidescontrols erosion of the topsoil, and produces oxygen. Furthermore, hemp can be used to replace many potentially harmful products, such as tree paper (the processing of which uses chlorine bleach, which results in the waste product polychlorinated dibensodioxins, popularly known as dioxins, which are carcinogenic, and contribute to deforestation, cosmetics, and plastics, most of which are petroleum-based and do not decompose easily. The strongest chemical needed to whiten the already light hemp paper is non-toxic hydrogen peroxide.
Hemp produces 4 times the raw material than trees for paper making. Hemp can be planted between 1-3 times a season, depending on location and can be recycled up to 10 times, compared to 3 or 4 for wood pulp paper. The same fibre products that the hemp harvest produces also provides raw-materials for a host of other sustainable products.
If today is a typical day on planet Earth, we will lose 116 square miles of rainforest, or about an acre a second. We will lose another 72 square miles to encroaching deserts, as a result of human mismanagement and overpopulation. We will lose 40 to 100 species, and no one knows whether the number is 40 or 100. Today the human population will increase by 250,000. And today we will add 2,700 tons of chlorofluorocarbons to the atmosphere and 15 million tons of carbon. Tonight the Earth will be a little hotter, it’s waters more acidic, and the fabric of life more threadbare.
Hemp’s been used for textiles since time immemorial–samples of hemp fabric in China date back to 8,000 BC–though it has certainly had a renaissance of late. Shedding the slightly rough and tough image it once had hemp has broken into the realms of high fashion, has been mixed with silk for lingerie, as well as being applied to more obvious applications where it’s durability is used to best advantage: Providing material for shoes, jeans, and other tough sport clothing.
Of all the uses for hemp, even if you only have a cursory knowledge of the subject you’re probably away of hemp fabric, clothing and paper, but here’s one that’s an eye-opener: Hemp provides all sorts of good building materials. You can make it into insulation as companies in the Netherlands and Ireland are doing. It can be used to make engineered building products like fiberboard and pressboard, and even be used to make ‘hempcrete‘, a stronger, lighter, and more environmentally friendly version of concrete.
Also, making biofuel from hemp is very possible! Like pretty much any vegetable oil you can take hemp oil and process it into biodiesel. You still have all the concerns about conversion of land that could be used for food production into land used to fuel vehicles, but the biodiesel process is certainly solid. As cellulosic ethanol technology becomes more commercial viable – something seemingly just over the horizon for a couple of years now – there’s no reason why you couldn’t utilize hemp stalks or other leftovers as a feedstock. Considering all that, it stands to reason that hemp could also be utilized to make liquid fuels that are chemically identical to petroleum-based gasoline or diesel as well
CBD (Cannabidiol) based e-liquids are growing more and more popular, and not only within the vaping community. It doesn’t come as a surprise, considering the various health benefits of CBD, legal status and more information available about this particular cannabis component.
Some of you (non-vapers) may ask: why vape CBD if there are other ways of taking it, for example CBd oil? CBD is usually taken orally as a cannabis-based concentrate or extract. However, compared to smoking or vaporizing, ingesting cannabinoids orally can cause inconsistent absorption and a delayed effect.
The study conducted experiments using combinations of purified THC and CBD, in order to determine the best way of administering CBD via vaporizer. Here’s what they found:
CBD begins to evaporate at a temperature of around 200°C (392°F), similar to THC, making it possible to release CBD as a gas without burning the plant matter. In the study, vaporizing at 230°C (446°F) seemed to release more CBD than vaporizing at 210°C (410°F).
At lower doses (4-8 mg), as much as 97% of CBD was vaporized. However, the conversion rate dropped significantly as the dose increased. At 200 mg, just 40% of CBD was converted to vapor. Interestingly, when administered together, the dose of CBD seemed to affect the conversion rate of THC. On average, 55% of THC was converted to vapor.
The researchers found 200 mg to be the maximum dose of CBD that could be vaporized efficiently, with higher doses producing a saturation effect. However, the point of CBD saturation seems to be related to the vaporizer and its heating efficiency, meaning that different vaporizers may allow for higher or lower doses to be vaporized at once.
So the answer is yes – vaping CBD e-liquid is safe. It even comes in the great flavours you know and love such as Lemon & Lime, Strawberry & Kiwi and many others. All you do is fill up your ecig and let the atomizer do its work. The atomizer will heat up your e-liquid and turn it into vapour, which you can inhale and enjoy!
Because of all the studies and research many people are now turning to CBD to help alleviate and treat a multitude of ailments and illness’s ranging from multiple sclerosis, severe epilepsy, certain cancers, pain and anxiety among others.
CBD has been overshadowed by tetrahydrocannabinol or THC, probably the better known compound in certain strains of cannabis. This is because unlike THC, CBD doesn’t produce a psychoactive high (so you do not feel “stoned”. However CBD has been known to have anti-epileptic, anti-spasmodic, antipsychotic and anti-anxiety, properties. (read our previous post on CBD and anxiety here)
There are of course lots more potential benefits for CBD (and THC!) and studies and research will long continue.
Vaping CBDeaze delivers totally organic cannabidiol through the buccal membranes in the mouth, and while we make no health claims about our CBD eliquid the growing amount of scientific research reflects both the health and medicinal benefits of CBD.
There is a staggering amount of people who suffer from chronic and constant pain which represents a massive public health issue Worldwide!
Studies show that CBD has an anti-inflammatory and analgesic effect on the CB1 receptor in the humans endocannabinoid system which can help ease chronic pain and inflammation, although we do not make any heath claims in to our eliquid we have in fact many people who vape CBDeaze report back to us that it helps with easing their ailments such as backpain, headaches etc as well as those who suffer from more severe pain such as multiple sclerosis (MS) and muscular pain issues in general.
Cannabis is a genus of a flowering plant which includes three different species within the “family” sativa, indica and ruderalis but all come under the Cannabaceae family.
For thousands of years this simple plant has been used for a multitude of applications (and no not just to get people high or stoned) it has been used for hemp fibres and oils for medicinal purposes, it has been selectively grown for various reasons and it continues to grow wild mainly in the Central Asian and Indian subcontinent and many tropical and humid parts of the World.
In this blog post we will focus on the three different species and how they differ from each other.
Cannabis sativa and indica are probably the best known of these three, with some studies suggesting that the sativa strain has higher levels of CBD (cannabidiol) and lower THC (tetrahydrocannabinol) whereas the indica variety is the opposite with higher THC (the pyschoactive compound which give that high feeling) and lower CBD. There is a suggestion that higher CBD to THC strains are less likely to cause anxiety and in our previous blog post we discussed studies showing that CBD (such as the CBD used in our cannabidiol eliquid) can potentially help relive anxiety. Both strains are used for a variety of reasons, including industrial (hemp fibre etc), medicinal (medical marijuana) and recreational (for the feeling) use.
Cannabis Ruderalis is a lesser known and certainly less common variety, and produces only trace amounts of THC and is very rarely used for industrial, medicinal or recreational use, in fact is mainly used in Russian and Mongolian folk medicine for treating depression as it originates from Central Russia.
CBDeaze is a cannabidiol eliquid formulated in the UK, containing no nicotine. It’s main purpose is to give vapers an alternative choice of eliquid over current nicotine eliquids.
It contains 100mg of organic CBD so you can enjoy a tasty all day vape with the potential health benefits of cannabidiol without the high feeling.
Have you ever got anxious? Ever had that horrible, nervous, worried “feel sick to the stomach” feeling of anxiety? Maybe you have felt it before a big event, public speaking in front of people, a presentation to the boss, a first date, or a number of normal human interactions that can make us feel anxious. Now imagine having that feeling all the time. Anxiety disorders are incredibly common.
Being at the forefront of of research in to cannabinoids for our CBD eliquid and working with them day in day out we are very much aware of the synthetic variety, what they are and where they come from!
We are also very much aware of how dangerous synthetic cannabinoids can be!
Synthetic cannabinoids are essentially man-made and in certain instances mind-altering chemicals that mimic natural cannabinoids found in cannabis and hemp and are sometimes sprayed on dried, shredded plant material so they can be smoked (previously sold as legal highs or more commonly known as spice in the UK) or sold as liquids which can be vaped or used as tinctures.
However organic natural cannabinoids and the synthetic kind are totally different because often they are “supersized” and made stronger then those found normally in marijuana or hemp and because of this fact, they may affect the brain much more powerfully and the actual effects can be unpredictable and, in some cases, severe or fatal.
Watch this short but powerful video from VICE about how synthetic “marijuana” can affect people
Here at CBDeaze we know there are so called CBD eliquids made with synthetic cannabidiol which are blatantly being sold at often cheap pricing (organic cannabidiol is not a cheap product hence why our cannabidiol ejuice is more expensive then your average nicotine based eliquid) with no thought nor care for where it ends up and if it potentially is dangerous for them – for these companies it is purely a profits game, with them jumping on “bandwagon” of this legitimate revolution to the vaping World, nicotine free organic cannabidiol eliquids available in the UK.
To read more about us, view our product liability status, our latest eliquid analysis or the official statement from the UK Home Office on the legal status of cannabidiol just click here
We always have and always will use 100% organic and natural cannabidiol in all of our products and will continue the fight against synthetic cannabinoids and further push and support the studies in to the valid health benefits of organic cannabinoids found in both the cannabis and hemp plant. We are not a “legal high” in fact vaping CBDeaze will not get you high or give you a stoned feeling (this is the THC element not CBD) it does however offer an alternative vaping experience with the added benefits of totally natural CBD.
Marijuana, cannabis, ganja, weed, pot, grass, dope, call it what you want but cannabis and hemp and their hundreds of different compounds like CBD and THC are quickly becoming one of the most promising new treatments for many sicknesses and ailments in humans.
But did you also know that cannabis and in this instance cannabidiol, (or CBD) also has potentially many benefits for your family pets.
As with the many studies into the benefits of cannabidiol to humans there are also studies beginning to start on the effects of CBD potentially being able to treat health conditions in animals as well such as anxiety, arthritis and cancer in dogs
There are also companies who have included CBD products aimed directly at the animal marketplace, such as American dog treat and chew manufacturer Barkworthies® who offer within their extensive natural and healthy range, a pumpkin cannabidiol dog treat.
As per Barkworthies® mission statement;
“At Barkworthies® we believe that simpler is better. Barkworthies treats and chews are completely digestible and contain absolutely no preservatives, chemicals, or additives. We only use the best ingredients and most of our products contain only a single ingredient. What could be simpler?”
“a great alternative snack for dogs who need a little something more. From mood disorders and pain to cardiac health and cancer, there are many reasons why these treats can benefit your special family member. These non-toxic, 100% legal treats contain a naturally occurring compound found in the cannabis plant, Cannabidiol (CBD). This plant extract is highly therapeutic, and can help relieve many common symptoms that affect dogs, including inflammation, lack of appetite and anxiety.
Barkworthies Pumpkin Cannabidiol Treats are made from all-natural ingredients, and are 100% safe – we hold our treats to human quality and safety standards. Our goal is to bring calm and vitality to your home by bringing happiness and health to your pets. Barkworthies Pumpkin Cannabidiol Treats are an ideal addition to the diet of your four-legged friend, and we feel confident that you will see the benefits for yourself.”